{"id":9281,"date":"2025-05-19T11:25:59","date_gmt":"2025-05-19T11:25:59","guid":{"rendered":"https:\/\/firearmman.com\/?p=9281"},"modified":"2025-05-19T11:26:01","modified_gmt":"2025-05-19T11:26:01","slug":"former-president-joe-bidens-cancer-diagnosis-what-does-a-gleason-score-of-9-mean","status":"publish","type":"post","link":"https:\/\/firearmman.com\/?p=9281","title":{"rendered":"Former President Joe Biden&#8217;s cancer diagnosis: What does a Gleason score of 9 mean?"},"content":{"rendered":"<div data-testid=\"prism-article-body\">\n<p class=\"EkqkG IGXmU nlgHS yuUao MvWXB TjIXL aGjvy ebVHC \">Former President Joe Biden is battling an &#8220;aggressive&#8221; form of <a class=\"zZygg UbGlr iFzkS qdXbA WCDhQ DbOXS tqUtK GpWVU iJYzE \" data-testid=\"prism-linkbase\" href=\"https:\/\/abcnews.go.com\/Politics\/former-president-joe-biden-diagnosed-prostate-cancer\/story?id=121932146\" target=\"_blank\">prostate cancer<\/a>, his office announced on Sunday, adding his condition is characterized by a &#8220;Gleason score of 9.&#8221;<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">His office also said Biden&#8217;s diagnosis included metastasis to the bone.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">Biden&#8217;s cancer diagnosis comes after a small nodule was found in the former president&#8217;s prostate after &#8220;a routine physical exam&#8221; on Tuesday. The discovery of the nodule &#8220;necessitated further evaluation,&#8221; his spokesperson said at the time.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">In February 2023 &#8212; while the now-82-year-old former president was serving in the White House &#8212; Biden had a lesion removed from his chest that was cancerous, according to the former White House physician. Additionally, before entering office, Biden had several non-melanoma skin cancers removed with Mohs surgery.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">As the world reacts to Biden&#8217;s medical news, ABC News has broken down what his condition means and what possible treatments can be done.<\/p>\n<h2 class=\"RxNCg ykkUm PvZ nIjPJ PMXYp LmsHF SfAHY mNgye lNbol LBPRq rBLIK \">What to know about prostate cancer<\/h2>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">Prostate cancer is a type of cancer that forms in the tissues of the prostate, the small gland in men&#8217;s prostate that produces semen, according to the National Institutes of Health (NIH)<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">It is the most common cancer and the second leading cause of cancer death among men in the U.S., according to the federal health agency.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">The NIH reports an estimated 313,780 new cases of prostate cancer will be diagnosed this year &#8212; representing over 15% of all new cancer cases.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">An estimated 35,770 deaths from prostate cancer will occur this year &#8212; representing 5.8% of all cancer deaths, according to the agency.<\/p>\n<div class=\"oLzSq QrHMO fnRUo pvsTF EhJPu vPlOC zNYgW OsTsW RMeqy daRVX ISNQ sKyCY eRftA acPPc MENS nFwaT MCnQE mEeeY SmBjI xegrY rPLsU iulOd NIuqO zzscu lzDCc aHUBM IEgzD OjMNy eQqcx SVqKB GQmdz jaoD VWDdR ONJdw vrZxD OnRTz gbbfF roDbV GPGwb oMlSS gfNzt oJhud eXZcf zhVlX \">\n<div>\n<div class=\"InlineImage GpQCA lZur asrEW \" data-testid=\"prism-inline-image\">\n<figure class=\"kzIjN GNmeK pYrtp dSqFO \" data-testid=\"prism-figure\">\n<div class=\"GpQCA lZur \" style=\"padding-bottom:66.69921875%\" data-testid=\"prism-ratio-frame\">\n<div class=\"FvQLF iLTd NqeUA UzzHi iWsMV \"><picture data-testid=\"prism-picture\"><source media=\"(max-width: 414px)\" srcset=\"https:\/\/i.abcnewsfe.com\/a\/5a816190-9863-4caa-b11c-fed050d79cfd\/biden_1747604941909_hpMain.jpg?w=375, https:\/\/i.abcnewsfe.com\/a\/5a816190-9863-4caa-b11c-fed050d79cfd\/biden_1747604941909_hpMain.jpg?w=750 2x\"\/><source media=\"(min-width: 415px)\" srcset=\"https:\/\/i.abcnewsfe.com\/a\/5a816190-9863-4caa-b11c-fed050d79cfd\/biden_1747604941909_hpMain.jpg?w=750, https:\/\/i.abcnewsfe.com\/a\/5a816190-9863-4caa-b11c-fed050d79cfd\/biden_1747604941909_hpMain.jpg?w=1500 2x\"\/><\/picture><\/div>\n<\/div><figcaption>\n<div class=\"nMMea bNYiy Mjgpa dGwha DDmxa jgKNG RGHCC aBIU PriDW lZur \" data-testid=\"prism-caption\">\n<p><span class=\"hsDdd OOSI GpQCA lZur VlFaz \" data-testid=\"prism-truncate\"><span><span class=\"gtOSm FbbUW tUtYa vOCwz EQwFq yCufu eEak Qmvg nyTIa SRXVc vzLa jgBfc WXDas CiUCW kqbG zrdEG txGfn ygKVe BbezD UOtxr CVfpq xijV soGRS XgdC sEIlf daWqJ \">U.S. President Joe Biden delivers remarks at a news conference at the Filoli Estate on November 15, 2023 in Woodside, California. The news conference follows a meeting between Biden and Chinese President Xi Jinping during the Asia-Pacific Economic Cooperation (APEC) Leaders&#8217; week, their first since meeting at the Indonesian island resort of Bali in November 2022. (Photo by Kent Nishimura\/Getty Images)<\/span><\/span><\/span><\/p>\n<p><span class=\"gtOSm FbbUW tUtYa vOCwz EQwFq yCufu eEak Qmvg nyTIa SRXVc vzLa jgBfc WXDas CiUCW kqbG zrdEG txGfn ygKVe BbezD UOtxr CVfpq xijV soGRS XgdC sEIlf daWqJ YNujN JGtjI aZFDu rkKLh \">Kent Nishimura\/Getty Images<\/span><\/p>\n<\/div>\n<\/figcaption><\/figure>\n<\/div>\n<\/div>\n<\/div>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">Prostate cancer has a five-year relative survival rate, meaning the percentage of people alive five years after diagnosis, is roughly 98%.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">Generally, prostate cancer usually grows very slowly and finding and treating it before symptoms occur may not improve men&#8217;s health or help them live longer.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">However, it is generally a more treatable type of cancer, even when it has spread further.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">Roughly 12.9% of men will be diagnosed with prostate cancer at some point in their lifetime, according to the NIH. In 2022, there were an estimated 3.5 million men living with prostate cancer in the United States.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">The median age of prostate cancer diagnosis is 68 years old, according to the agency, while the median age of prostate cancer death is 79.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">While the agency reports rates for new prostate cancer cases have been rising an average 1.8% each year over from 2013 to 2022, death rates have been falling on average 0.6% each year over between 2014 and 2023.<\/p>\n<h2 class=\"RxNCg ykkUm PvZ nIjPJ PMXYp LmsHF SfAHY mNgye lNbol LBPRq rBLIK \">What is a Gleason score?<\/h2>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">The Gleason grading system, or Gleason score, refers to how likely the cancer is to advance and spread, but does not predict the outcome.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">It&#8217;s way of describing prostate cancer based on how abnormal the cancer cells in a biopsy sample look under a microscope and how quickly they are likely to grow and spread, according to the NIH.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">The Gleason score is calculated by adding together the two grades of cancer cells that make up the largest areas of the biopsied tissue sample, the NIH says.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">The grading system usually ranges from 6 to 10.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">Biden&#8217;s diagnosis of a Gleason score of 9 indicates his cancer is aggressive.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">A score of 9 indicates that the cancer cells look very different from normal prostate cells and are likely to grow and spread rapidly. This places the cancer in Grade Group 5, the highest risk category, associated with a greater likelihood of metastasis and a more challenging prognosis. Yet, despite the cancer&#8217;s apparent aggressiveness, its hormone-sensitive nature offers a viable treatment pathway.<\/p>\n<h2 class=\"RxNCg ykkUm PvZ nIjPJ PMXYp LmsHF SfAHY mNgye lNbol LBPRq rBLIK \">Possible treatment options<\/h2>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">While Biden&#8217;s official treatment plan remains to be announced, possible options for the former president include hormone therapy, or androgen deprivation therapy (ADT), which can reduce levels of male hormones that can fuel prostate cancer growth.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">This approach can effectively slow disease progression and manage symptoms, even in advanced stages where the cancer has spread to the bones.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">Regular monitoring of prostate-specific antigen (PSA) levels is crucial, as rising PSA levels can indicate cancer activity and help assess treatment effectiveness.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">Surgery is typically not an option in cases like Biden&#8217;s, when the disease has spread to the bone and is not confined to the prostate.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">Following the former president&#8217;s diagnosis, the American Cancer Society released a statement, saying, &#8220;This news is a reminder about the tragic impact of prostate cancer in the U.S.&#8221;<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">&#8220;Early detection is key, and we are concerned given the 5% year-over-year increase in diagnosis of men with more advanced disease. We can and must do more to prevent late-stage diagnosis and death from prostate cancer,&#8221; the ACS said.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC eTIW sUzSN \">Futher resources are available at the American Cancer Socity&#8217;s 24\/7 cancer helpline (1-800-227-2345) and website, <a class=\"zZygg UbGlr iFzkS qdXbA WCDhQ DbOXS tqUtK GpWVU iJYzE \" data-testid=\"prism-linkbase\" href=\"https:\/\/abcnews.go.com\/Politics\/former-president-joe-bidens-cancer-diagnosis-gleason-score\/cancer.org\" target=\"_blank\">cancer.org<\/a>.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Former President Joe Biden is battling an &#8220;aggressive&#8221; form of prostate cancer, his office announced on Sunday, adding his condition is characterized by a &#8220;Gleason score of 9.&#8221; His office also said Biden&#8217;s diagnosis included metastasis to the bone. Biden&#8217;s cancer diagnosis comes after a small nodule was found in the former president&#8217;s prostate after [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":9282,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[],"class_list":["post-9281","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-us-news"],"_links":{"self":[{"href":"https:\/\/firearmman.com\/index.php?rest_route=\/wp\/v2\/posts\/9281","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/firearmman.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/firearmman.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/firearmman.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/firearmman.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=9281"}],"version-history":[{"count":1,"href":"https:\/\/firearmman.com\/index.php?rest_route=\/wp\/v2\/posts\/9281\/revisions"}],"predecessor-version":[{"id":9283,"href":"https:\/\/firearmman.com\/index.php?rest_route=\/wp\/v2\/posts\/9281\/revisions\/9283"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/firearmman.com\/index.php?rest_route=\/wp\/v2\/media\/9282"}],"wp:attachment":[{"href":"https:\/\/firearmman.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=9281"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/firearmman.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=9281"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/firearmman.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=9281"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}